By muscle morphology, histopathology, and biochemical study, numerous researches have been done on the paraspinal muscle of AIS patients. Abnormal findings include increased EMG activity on the convexity of the curve; decreased type II fibers near the apex and at the convex side; swollen mitochondria, myofibrillar damage, disruption of myofibrillar banding pattern and loss of myofilaments under electron microscopy; increased intracellular lipid and glycogen; increased intracellular calcium; decreased number of muscle spindles; abnormalities in muscle enzyme activity; abnormalities in muscle protein synthesis and decrease in zinc content in muscle.
The current view held by most investigators is that the observed abnormalities in the muscle are more likely to be secondary to the spinal deformity rather than as a primary cause
no subject
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Skeletal Muscle Abnormality
By muscle morphology, histopathology, and biochemical study, numerous researches have been done on the paraspinal muscle of AIS patients. Abnormal findings include increased EMG activity on the convexity of the
curve; decreased type II fibers near the apex and at the convex side; swollen mitochondria, myofibrillar damage, disruption of myofibrillar banding pattern and loss of myofilaments under electron microscopy; increased intracellular lipid and glycogen; increased intracellular
calcium; decreased number of muscle spindles; abnormalities in muscle enzyme activity; abnormalities in muscle protein synthesis and decrease in zinc content in muscle.
The current view held by most investigators is that the observed abnormalities in the muscle are more likely to be secondary to the spinal deformity rather than as a primary cause